Research use only. Not for use in humans or animals. All products and information on this site are provided strictly for in-vitro laboratory research purposes. They are not for use in humans or animals, and are not drugs, foods, cosmetics, or medical devices.
What Is Ipamorelin? A Research Peptide Overview
Ipamorelin is a synthetic pentapeptide studied as a selective agonist of the GHS-receptor receptor (GHS-R) — the same receptor that the hormone ghrelin acts on. It belongs to the GH-secretagogue family of research peptides and is best known for being studied alongside CJC-1295. This overview covers what ipamorelin is, how it differs from GHRH analogs, and how to source research-grade material.
Ipamorelin at a glance
| Property | Value |
|---|---|
| Name | Ipamorelin |
| Class | Selective GHS-receptor (ghrelin-receptor) agonist |
| Type | Synthetic pentapeptide |
| Sequence | Aib-His-D-2-Nal-D-Phe-Lys-NH₂ |
| Appearance | White lyophilized powder |
Two families of GH secretagogue
GH-secretagogue research peptides fall into two families that act on different receptors:
- GHRH analogs — sermorelin, CJC-1295, tesamorelin — act on the GHRH receptor.
- GHS-receptor agonists — ipamorelin, GHRP-2, GHRP-6 — act on the GHS (ghrelin) receptor.
Ipamorelin is notable within the GHS-receptor family for its selectivity: it is studied as one of the more selective agonists, without the broader signaling seen with some earlier GHRPs.
Why ipamorelin is studied with CJC-1295
Because ipamorelin (GHS receptor) and CJC-1295 (GHRH receptor) act on complementary pathways, they are a common research pairing. Studies use the combination to examine how simultaneous engagement of both receptor families differs from either alone. See what is CJC-1295 →.
What ipamorelin is studied for
In laboratory and preclinical research, ipamorelin is studied for:
- GHS-receptor signaling — selective agonist pharmacology.
- Somatotroph response in endocrine-model systems.
- Comparative secretagogue research — selectivity versus earlier GHRPs.
Ipamorelin offered here is a research chemical for laboratory use only. Not for use in humans or animals.
Ipamorelin ships as a lyophilized (freeze-dried) powder. Researchers refer to the lot-specific COA and validated laboratory protocols for any handling observations.
How research-grade material is verified
Every batch from a credible US supplier should arrive with a third-party Certificate of Analysis (COA) for that exact lot. Peptide Technologies publishes a COA on every batch and ties it to a QR code on the vial. A complete COA reports:
- Identity — mass spectrometry (ESI-MS) confirming the observed mass matches the theoretical mass of the target sequence.
- Purity — reverse-phase HPLC, reported as percent peak area at a fixed wavelength (typically 220 nm). Research-grade material is ≥99% by area.
- Net content — gravimetric confirmation the vial holds the stated mass within tolerance.
- Endotoxin — LAL assay below research-grade thresholds.
If a vendor cannot show a lot-specific COA, you cannot verify what is in the vial. Browse the full COA library →
How to source research-grade material
For laboratory research, sourcing quality comes down to a few checks:
- Lot-specific COA from an accredited, independent laboratory — not a generic marketing PDF.
- HPLC purity ≥99% by peak area, with the chromatogram shown.
- US synthesis and finishing, so the chain of custody is documented end to end.
- Cold-chain shipping for lyophilized material, so the product arrives stable.
Peptide Technologies meets each of these and publishes a third-party COA for every lot. Browse the public COA library →
FAQ
What is ipamorelin?
Ipamorelin is a synthetic pentapeptide studied as a selective agonist of the GHS-receptor (ghrelin) receptor, used in endocrine research.
How is ipamorelin different from sermorelin?
They act on different receptors: ipamorelin on the GHS (ghrelin) receptor, sermorelin on the GHRH receptor. This is why they are sometimes studied together.
Why is ipamorelin studied with CJC-1295?
Ipamorelin (GHS receptor) and CJC-1295 (GHRH receptor) act through complementary pathways, making them a common research pairing.
How is ipamorelin verified?
Research-grade ipamorelin is verified by HPLC for purity, mass spectrometry for identity, and an LAL endotoxin assay, reported on a lot-specific third-party COA.
Is ipamorelin a research chemical?
Yes. Ipamorelin supplied by Peptide Technologies is a research chemical for laboratory use only. Not for use in humans or animals.